Requires a spear.

A melee attack with 140% poison chance.

Poisons inflicted by serpent strike last 40% longer.

More information

Poison chance above 100% gives a chance to apply additional stacks of poison (this mechanic applies to all hits, not just Serpent Strike).

Added damage is applied at 100% effectiveness.

The strength of the python and the venom of the cobra are yours to channel

Effect

Base damage per hit
2 Physical
Critical strike chance
5 % · 200% critical damage
Added damage effectiveness
100 %
Counts as
Melee

Applies: Poison (140 %)

Base values before skill tree nodes, passives and gear.

Skill tree: Serpent Strike

The skill tree as it appears in game. A specialized skill gains one point per level up to level 20; the number on a connection shows how many points the previous node needs.

Hover or tap a node for its description. The number on a node is its maximum points.

All nodes as a list (29)
  1. Primal Serpent max 1

    When Serpent Strike kills an enemy or hits a rare or boss enemy, you have a chance to summon a Primal Serpent.

    • 1 Maximum Primal Serpents
    • 12% Summon Chance on Kill
    • 2% Summon Chance on Rare or Boss Hit

    Requires 2 points in Culling Point

  2. Culling Point max 3

    Serpent Strike hits have a chance to instantly kill enemies that are below a threshold (a percentage of their maximum health).

    • 6% Kill Threshold

    If you have a similar effect from an item or passive node, then the highest threshold is used.

  3. Coldfang max 5

    Serpent Strike hits have a higher chance to freeze enemies.

    • +20 Freeze Rate

    Requires Frostwyrm's Fury

  4. Serpent Venom max 2

    Serpent Strike hits have a chance to inflict Serpent Venom, an ailment that deals poison damage over time and prevents enemies from landing critical strikes. It lasts 3 seconds and cannot stack.

    • 50% Serpent Venom Chance

    Requires 2 points in Poison Tipped

  5. Spirit Viper max 1

    Serpent Venom deals more damage (multiplicative with other modifiers) based on your Vitality, and if you have 50 Vitality you regain mana when you inflict an enemy with Serpent Venom or refresh its duration.

    • +2% Serpent Venom Damage per Vitality
    • 1 Mana Gain with at least 50 Vitality

    Requires Serpent Venom

  6. Poison Tipped max 5

    Serpent Strike hits have a higher chance to poison on hit and they deal more melee damage per stack of poison on the target, up to a limit.

    • +8% Poison Chance
    • +1% Melee Damage Per Poison
    • +12% Max Melee Damage Bonus
  7. Venomous Union max 1

    When you lunge forwards with Serpent Strike, if you have a Scorpion it casts its companion ability, Venom Nova, twice, once centred on itself, and once centred on you.

    This effect has a 12 second cooldown, but ignores Venom Nova's regular cooldown and does not put it on cooldown.

    • 2 Venom Novas on Lunge (12 Second Cooldown)

    Requires Cobra Lunge

  8. Cobra Lunge max 1

    When you attempt to use Serpent Strike against a target that is slightly out of range you will lunge forwards before attacking.

    • Lunge if Slightly Out of Range

    Requires 2 points in Constrictor

  9. Constrictor max 5

    You gain a stack of Constrictor every 0.5 seconds, up to a maximum of 4. When you use Serpent Strike all stacks are consumed causing the attack to deal more damage per stack (multiplicative with other modifiers).

    • 5% Damage per Stack Consumed
    • 1 Stacks Gained per 0.5 Seconds fixed
    • 4 Max Constrictor Stacks fixed

    Requires Culling Point

    The stacks are not multiplicative with each other.

  10. Mussurana max 3

    Each stack of Constrictor also grants Serpent Strike additional poison chance and increased poison duration when consumed

    • +16% Poison Chance per Stack
    • +4% Poison Duration per Stack

    Requires 2 points in Constrictor

  11. Sapping Coils max 2

    You regain mana when you consume a stack of Constrictor.

    • 1 Mana per Stack Consumed

    Requires Mussurana

  12. Slither max 3

    You gain Slither for 4 seconds when you use Serpent Strike and hit at least one enemy.

    Each stack grants you more dodge rating (multiplicative with other modifiers).

    • 1 Slither Max Stacks
    • +10% Slither Dodge Rating
  13. Gouging Spear max 5

    Serpent Strike hits have a chance to cause enemies to bleed.

    • +20% Bleed Chance

    Requires Slither or Hydra Strikes

  14. Hydra Strikes max 3

    Serpent Strike has increased attack speed.

    • +5% Attack Speed

    Requires Gouging Spear or Poison Tipped

  15. Corrosive Venom max 5

    Serpent Strike hits have a chance to shred enemy armor.

    • +20% Armor Shred Chance

    Requires 2 points in Hydra Strikes

  16. Devour Prey max 2

    You regain health when Serpent Strikes kills or critically strikes an enemy.

    • 6 Health Gained On Kill
    • 6 Health Gained On Crit

    Requires 2 points in Slither or 2 points in Culling Point

  17. Eye of the Viper max 3

    Serpent Strike's critical strikes deal more damage.

    • +25% Critical Multiplier

    Requires Devour Prey

  18. Frostwyrm's Fury max 1

    Serpent Strike now has a chance to freeze and its base physical damage is converted to cold damage. Consequently this damage scales with increases to cold damage, but not increases to physical damage.

    Bleed chance from all sources is converted to Frostbite chance.

    • 100% Base Damage -> Cold
    • 40 Freeze Rate
    • Bleed Chance -> Frostbite

    Requires 2 points in Gouging Spear

  19. Vicious Strikes max 3

    Primal Serpents have increased melee attack speed and are granted health when they hit enemies with a melee attack.

    • +10% Primal Serpent Attack Speed
    • 10 Primal Serpent Health Granted On Melee Hit

    Requires Primal Serpent

  20. Iron Scales max 3

    Primal Serpents have more health (multiplicative with other modifiers) and additional armor

    • +60% Primal Serpent Health
    • +160 Primal Serpent Armor

    Requires Vicious Strikes

  21. Emerald Fangs max 3

    Primal Serpents's hits have an additional chance to poison enemies and inflict frailty.

    • +35% Primal Serpent Poison Chance
    • +35% Primal Serpent Frailty Chance

    Requires Vicious Strikes

  22. Guardian Spear max 1

    Instead of summoning a new serpent when the Primal Serpent node's effect triggers, you heal your current serpent to full health and it deals more damage (multiplicative with other modifiers) for 10 seconds. This damage buff can stack.

    • Heal Serpent Instead of Resummoning
    • 65% Serpent Damage Buff on Heal
    • 10 Damage Buff Duration (Seconds)

    Requires Primal Serpent

    This effect triggers when you kill an enemy and roll to summon.

  23. Biting Winds max 3

    Frostbite inflicted by Serpent Strike lasts longer and has additional cold penetration

    • +15% Cold Penetration with Frostbite
    • +15% Frostbite Duration

    Requires Coldfang

  24. Shroud of Winter max 1

    You have additional dodge rating per cold resistance, for each stack of the Slither buff.

    • +1 Dodge Rating Per 1% Cold Resistance

    Requires 3 points in Coldfang

  25. Swirling Carnage max 1

    Each active stack of Maelstrom grants Serpent Strike additional chance to inflict bleed on hit and more damage over time (multiplicative with other modifiers).

    • +2% Bleed Chance per Maelstrom
    • +2% Damage over Time per Maelstrom

    Requires 3 points in Gouging Spear

  26. Steel Eater max 1

    Armor Shred inflicted by Serpent Strike has an increased effect based on your Dexterity.

    • +4% Armor Shred Effect per Dexterity

    Requires 3 points in Corrosive Venom

  27. Shattered Immunity max 3

    Serpent Venom deals more damage (multiplicative with other modifiers) based on the number of poison and frostbite stacks on them, up to a maximum benefit from each ailment.

    • +1% Serpent Venom Damage Per Poison
    • +1% Serpent Venom Damage Per Frostbite Stack
    • +100% Maximum Benefit per Ailment

    Requires Serpent Venom

    For example with 2 points invested, you can receive up to 200% more damage from poison by having 100 poison stacks on the enemy, and up to 200% more damage from frostbite by having 100 frostbite stacks on the enemy.

  28. Fast Acting Toxins max 1

    Serpent Venom deals more damage (multiplicative with other modifiers) based on your melee critical strike chance.

    If your melee crit chance is above 50% then Serpent Venom deals its damage twice as quickly. This does not increase the total damage it deals over its full duration, but rather halves its duration and doubles its damage per second.

    • +2% Serpent Venom Damage per Melee Crit Chance
    • +100% Serpent Venom Speed with >50% Melee Crit Chance

    Requires Shattered Immunity or Spirit Viper

  29. Dread Fang max 3

    Ailments applied by Serpent Strike and Primal Serpents have additional poison penetration.

    • +15% Poison Penetration

    Requires Serpent Venom

More skills: Primalist

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